The problem is, in order to attract people from a distance to entry level jobs or low skilled jobs (such as warehouse), you have to significantly increase the pay. When you significantly increase the pay, you hurt the profitability metric (whatever index the company uses) and a city with higher employment could be more attractive due to lower pay.
It's all a ratio..
Cost of increased transportation to access the highway system + lower pay = X
Cost of lower transportation costs to access highway + higher pay = Y
Many more factors to consider of course, but yes there is a point where a very low unemployment rate can negatively affect a relocation or expansion.
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