Santa Fe -- it is right at 8 hours. We drive there twice per year generally, once by ourselves then the other time over Thanksgiving with our three kids. We love it out there. Santa Fe has excellent restaurants, museums, art exhibits, and great little shops to peruse through by foot. We always stay there downtown at the Plaza area as you can just park your car and walk pretty much the whole time you're there. There are several churches you can go into and check out that have been there for centuries. If you want to see some beautiful Rocky Mountain scenery, you can drive the high road to taos and take in some breathtakingly sweeping views. We will generally drive out there on a Thursday, spend Friday and Saturday there, then drive home on Sunday. Amarillo is right there at the four-hour mark halfway and has lots of places to stretch your legs and eat lunch on the way out there and on the way back.