View Full Version : COVID: Vaccine?



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HangryHippo
12-09-2020, 07:47 PM
No but all the month long symptoms fit. I broke my collarbone in 1980 during a bike race and I wouldn't have to have an x-ray to know if I ever broke it again. I know what it felt like. When I have been fever free for 14 days per OBI guidelines I'll donate blood and I'm 99.9% sure I'll test positive for antibodies again.
You kept describing lingering symptoms for some time. Is it possible that you’re a long-hauler as opposed to a second case (which seems unlikely considering your original disease timeline)?

Bill Robertson
12-09-2020, 08:18 PM
You kept describing lingering symptoms for some time. Is it possible that you’re a long-hauler as opposed to a second case (which seems unlikely considering your original disease timeline)?I don't think so. One, I haven't seen reports of long haul continuation happening 8 months after the first time. Two, there was a visitor at work that tested positive after returning home right about then. I could have easily been in hallways, restrooms, etc. right after him. His time there would be right on for my onset. Sadly, his stay was the one time they tried opening the place since March. Before that week and since the building has had like 5 people out of 40 working daily. So I can go all day and see no one. Except that one week. Also, I didn't say but maybe I should have but this second time my wife developed very similar symptoms just about 10 days after I did so that unfortunately fits with me passing it to her. Right now our big thing is who's going to go to the kitchen for bottled water since it will require a rest afterward.

PaddyShack
12-10-2020, 09:05 AM
So, how longs does the vaccine prevent someone from getting covid-19? If those antibodies from having covid-19 wear off after some time, wouldn't the antibodies from the vaccine do the same? My understanding of vaccines is that it is just enough of the virus strand to trigger antibody production with out actually causing the full blown symptoms of the full strength virus, it doesn't sound much different whether you get COVID or the vaccine, both generate the antibodies, which leads to better response when the virus comes around to your body again.

PoliSciGuy
12-10-2020, 09:10 AM
So, how does the vaccine prevent someone from getting covid-19 if those antibodies from having covid-19 wear off after some time, my understanding of vaccines is that it is just enough of the virus strand to trigger antibody production with out actually causing the full blown symptoms of the full strength virus.

Depends on the technology. mRNA vaccines don't have any live virus but rather simply send a message (in incredibly layman's terms) to our antibodies to prep a defense against COVID-19. As for immunity, it will most likely last years according to recent studies: https://www.nytimes.com/2020/11/17/health/coronavirus-immunity.html

I fully expect I'll have to take multiple COVID vaccine shots throughout my life, but not nearly as often as a flu shot.

jedicurt
12-10-2020, 10:20 AM
So, how longs does the vaccine prevent someone from getting covid-19? If those antibodies from having covid-19 wear off after some time, wouldn't the antibodies from the vaccine do the same? My understanding of vaccines is that it is just enough of the virus strand to trigger antibody production with out actually causing the full blown symptoms of the full strength virus, it doesn't sound much different whether you get COVID or the vaccine, both generate the antibodies, which leads to better response when the virus comes around to your body again.

so there is some truth to this. a recent study. i can't find the actual study, but Science Versus just did a podcast on it. talking about how we still don't know how long the antibodies stay around, but we do know that there is a certain and small percentage that is able to get it a second time within about a 90 day window, but that appears to be a small percentage. and much like if you do get it and get it a second time, most see a milder case, but there is a small percentage of that subset that actually gets it quite a bit worse. But what appears to be more common are people who get it and it keeps flaring up and they have it for a month or even a few months... this seems to be a much larger issue and why a vaccine is a much better method for getting the antibodies than just getting the virus

jedicurt
12-10-2020, 10:24 AM
I fully expect I'll have to take multiple COVID vaccine shots throughout my life, but not nearly as often as a flu shot.

yep. i see it like tetanus , and you will need a booster every couple of years, or something. i hope i'm wrong, and even if you do, that still doesn't mean we can't keep working to eradicate it eventually one day (why i am so glad we now won't be leaving the WHO. we pay more because you get to say what that extra money goes to, and the US usually puts it into eradicating viruses. we are very close to getting Polio eradicated, and that would have stopped with us so close had we left.)

OkiePoke
12-10-2020, 12:54 PM
yep. i see it like tetanus , and you will need a booster every couple of years, or something. i hope i'm wrong, and even if you do, that still doesn't mean we can't keep working to eradicate it eventually one day (why i am so glad we now won't be leaving the WHO. we pay more because you get to say what that extra money goes to, and the US usually puts it into eradicating viruses. we are very close to getting Polio eradicated, and that would have stopped with us so close had we left.)

Funny thing about the tetanus booster is, they aren't sure how long it lasts (recently suggests 30 yrs), but no real study longer than 10 years.

jn1780
12-14-2020, 08:34 AM
Average time for coronavirus antibodies to wear off is about 4 - 5 years, but usually the population is not sick at the same time because a virus is not novel like covid-19 is.

There are a lot of viruses in the world that it would be "nice to remove from the world" , the human body is able to deal with 99% of those. Unfortunately we all get old, and our body takes more and more "refresher" courses in order to properly deal with viruses. Eventually, we get to the point where even the common cold can take us down. I don't think we can eliminate all viruses and bacteria from the world unless we do it somehow with Nanorobotics. But that seems like a huge can of worms we're opening up there.

HangryHippo
12-14-2020, 08:44 AM
Average time for coronavirus antibodies to wear off is about 4 - 5 years, but unlike a novel virus the population is not getting re-inoculated or re-infected at the same time which is what makes this virus so bad.

There are a lot of viruses in the world that it would be "nice to remove from the world" , the human body is able to deal with 99% of those. Unfortunately we all get old, and our body takes more and more "refresher" courses in order to properly deal with viruses. Eventually, we get to the point where even the common cold can take us down. I don't think we can eliminate all viruses and bacteria from the world unless we do it somehow with Nanorobotics somehow. But that seems like a huge can of worms we're opening up there.
Where in the world did you get 4-5 years? They have no way of knowing that yet. Or are you talking about a different coronavirus?

jn1780
12-14-2020, 08:51 AM
Where in the world did you get 4-5 years? They have no way of knowing that yet. Or are you talking about a different coronavirus?

Coronaviruses in general lasts an average 4-5 years on past research.

Bill Robertson
12-14-2020, 09:44 AM
Coronaviruses in general lasts an average 4-5 years on past research.
The antibodies for this seem to be lasting 3 to 4 months. This according to current research and personal experience.

PoliSciGuy
12-14-2020, 10:02 AM
The antibodies for this seem to be lasting 3 to 4 months. This according to current research and personal experience.

Yeah the antibodies only last for a few months, but the T-cell memory, which works to prevent re-infection, is likely to last years:

https://www.nature.com/articles/s41591-020-01143-2

https://www.biorxiv.org/content/10.1101/2020.11.15.383323v1

https://www.nytimes.com/2020/11/17/health/coronavirus-immunity.html

silvergrove
12-14-2020, 01:19 PM
Where in the world did you get 4-5 years? They have no way of knowing that yet. Or are you talking about a different coronavirus?

There are other coronaviruses besides the current pandemic one (The one that causes COVID-19 is called SARS-CoV-2). Other coronaviruses can cause mild to moderate respiratory illnesses, not unlike the common cold. Since they're all in the same family, we're making assumptions on how SARS-CoV-2 may act.

TheTravellers
12-17-2020, 10:48 AM
Hadn't really read this anywhere, and assumed that the COVID-19 vaccine would prevent a vaccinated person from getting infected, but that's apparently not the case (as it normally is with vaccines). It can prevent serious disease symptoms, but apparently can't prevent you from getting infected, so it's definitely not the silver bullet everybody's expecting.

jerrywall
12-17-2020, 10:53 AM
Hadn't really read this anywhere, and assumed that the COVID-19 vaccine would prevent a vaccinated person from getting infected, but that's apparently not the case (as it normally is with vaccines). It can prevent serious disease symptoms, but apparently can't prevent you from getting infected, so it's definitely not the silver bullet everybody's expecting.

Yeah. My sister works at Integris and got the vaccine yesterday, so I asked her if that meant I could see her at Christmas, and she said that what they're telling them is that even once they get the second shot, they don't know yet if folks could still spread it to others.

Pete
12-17-2020, 11:03 AM
Yeah. My sister works at Integris and got the vaccine yesterday, so I asked her if that meant I could see her at Christmas, and she said that what they're telling them is that even once they get the second shot, they don't know yet if folks could still spread it to others.

That's a pretty big deal.

Because even if vaccinated you could still transmit to others and we all know 1) it will take time to get a vaccination to the masses; and 2) there will be a lot of people who will elect not to take it.

PoliSciGuy
12-17-2020, 11:14 AM
I *believe* the Moderna vaccine showed it reduced spread, while the Pfizer data was inconclusive.

E: yeah, here - https://www.nytimes.com/2020/12/15/health/covid-moderna-vaccine.html

“ New data from Moderna suggest that its vaccine may reduce transmission. Researchers found that people who had one shot were less likely than those in the placebo group to have symptom-free infections in their noses — and therefore less likely to be contagious.”

jerrywall
12-17-2020, 11:22 AM
I'm *hoping* they're just showing an abundance of caution, and it will be much more effective at preventing spread than they're cautioning. I noticed this graphic (from the NYTs I think) just now that's saying the same stuff.

16629

Pete
12-17-2020, 11:22 AM
^

"Less likely to be contagious" is very far from not being contagious at all.

And I doubt many people are going to make that distinction, causing the inoculated to be more brazen and possibly infect others.


Hopefully over time, we'll have better data.